Rh(D) Immunoglobulin-VF (Anti-D) in 2mL vial (with variable volume inside)
250 IU and 625 IU of anti-D antibody for intramuscular use. (In other countries this would be referred to as 50 micrograms and 125 micrograms respectively.)
If Anti-D needs to be given intravenously (large doses or thrombocytopenia)
If Anti-D is given for large fetomaternal bleeds, febrile reactions due to haemolysis of the Rh(D) positive cells are common. Consider pre-medicating with paracetamol and ensure the patient is well hydrated.
Read manufacturer's instructions carefully
Always observe for turbidity, floating material and sediment
Intra-muscular use - follow recommended best practice.
Specific information is given in the manufacturer's product information
Although the manufacturer has raised concerns about giving Anti-D to women with a BMI greater than 30
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